Foghorn Therapeutics HQ Breaks Ground

Mary Beth Brown, Fanny Cavalié, Chris Maciejczak, Alex Main, Ron Ashton, Tim White, Bill Olson, Leanne Smith, Marc Consalvi, Matthew Walfield, and John Wise / Photo courtesy of Combrink Commercial

Cambridge, MA – Foghorn Therapeutics, located in Winchester, has selected Wise Construction to build its new Kendall Square headquarters.

On Jan. 10, the entire project team, including Alexandria Real Estate Equities, CBRE, Wise Construction, Tria, R.W. Sullivan, and Code Red Consultants, gathered to celebrate the occasion with a groundbreaking ceremony.

Foghorn, a Flagship Pioneering company, was founded in 2016 by Cigall Kadoch, Ph.D., Gerald Crabtree, M.D., and Doug Cole, M.D.

The firm is advancing a new class of medicines targeting diseases with genetically determined dependencies in the chromatin regulatory system.

Located at 500 Technology Square, the new headquarters will span more than 60,000sf over three floors, with further expansion planned over time. The project is being completed in two phases on a fast-track schedule. The updated space will include biology labs and chemistry labs, as well as open-space offices, huddle rooms, conference rooms, and an employee café.

To help with the challenges of a fast-track schedule, Wise was brought in early for preconstruction and developed a 3D model of the space using its in-house BIM modeling team. The model reveals existing conditions and the current building systems. This information helps the entire team including key subcontractors to understand the entirety of the space from the inside out before construction even begins.

Ceiling height is a critical point on this project due to the lab requirements. By having knowledge of the preexisting conditions before design was completed, the team has been able to maximize ceiling heights aligning mechanicals with the existing systems. By incorporating the prefabricated mechanical systems, Wise is able to build efficiencies into the schedule ensuring on-time completion.