DPS to Design Two Facilities

| January 10, 2019

Brammer Cambridge / photos by Brammer Bio

Boston – DPS Group, a privately-owned, global engineering, procurement, construction management and validation  firm, has been selected to design two cGMP manufacturing facilities for Brammer Bio, an industry leading viral vector contract development and manufacturing organization.

Brammer enables pharmaceutical and biotech innovators to translate proprietary gene therapy and gene-modified cell therapy technologies into novel treatments for patients through the development and manufacture of viral vectors.

DPS Group is designing an 8,000sf renovation of Brammer’s commercial cGMP facility located in Cambridge, Part of a larger 66,000sf building, the new space will increase the number of commercial suites, providing Brammer with additional capacity to produce treatments for a wider array of biotech companies.


DPS Group also is providing detailed design services to assist Brammer in developing a new cGMP manufacturing and quality control (QC) operations facility in an existing 50,000sf building in Lexington, As the company’s second commercial facility, the 35,000sf  build-out will support cGMP viral vector manufacturing with an associated fill/finish area, QC/micro and process establishment (PE) scale-up lab space, and warehouse for both cGMP and general operations.

DPS Group’s design affiliateTRIA, a partner-led architecture firm, is designing a 15,000sf office space as the second phase of the Lexington facility.

DPS Group faced several upfront challenges with the Cambridge project, including designing the highly flexible and adaptable suites within the 8,000sf footprint and minimizing operational impacts to other production, office and lab areas in the building during construction

To address ceiling constraints for utilities in the Lexington building, DPS Group is devising a new platform of interstitial ceiling space to support the Lexington facility’s additional air handlers and chillers. The solution provides Brammer with infrastructure flexibility in the future. Each of the production suites in the facility can be run in either upstream or downstream mode with larger suites accommodating multiple trains in parallel.



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Category: All, Life Science

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